Applications of Fluorine Compounds in Analytical Chemistry
نویسندگان
چکیده
منابع مشابه
Fluorine in medicinal chemistry.
Fluorinated compounds are synthesized in pharmaceutical research on a routine basis and many marketed compounds contain fluorine. The present review summarizes some of the most frequently employed strategies for using fluorine substituents in medicinal chemistry. Quite often, fluorine is introduced to improve the metabolic stability by blocking metabolically labile sites. However, fluorine can ...
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Since its first use in the steroid field in the late 1950s, the use of fluorine in medicinal chemistry has become commonplace, with the small electronegative fluorine atom being a key part of the medicinal chemist's repertoire of substitutions used to modulate all aspects of molecular properties including potency, physical chemistry and pharmacokinetics. This review will highlight the special n...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1986
ISSN: 1884-2003
DOI: 10.5650/jos1956.35.601